... headaches associated with menopause. However, these uses are based on a misconception that wild yam contains hormones or hormonal precursors ... Kokoro. The sugar-free (aglycone), diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and ... effects. Dioscorea is antispasmodic, and could be helpful for nausea of pregnant women(morning sickness), spasmodic hiccough and ...