... Group NegativeAccord with demandConclusionUp to gradeApplication: (1) Cosmetics: Kojic acid, (5-hydroxy-2-hydroxymethyl-1,4-pyrone, CAS: 501- ... , so it can largely inhibit the skin melanin formation; furthermore, kojic acid is safe and nontoxic and won’t cause white ... , liquid cream and skin cream. Whitening cosmetics containing kojic acid are able to treat effectively the freckle, senile plaque, ...