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Simvastatin is a hypolipidemic drug used to control elevated cholesterol, or hypercholesterolemia.
Simvastatin (INN) is a hypolipidemic drug used to control elevated cholesterol, or hypercholesterolemia. It is a member of the statin class of pharmaceuticals.
Simvastatin is a synthetic derivate of a fermentation product of Aspergillus terreus. The drug is marketed under the trade name Zocor, as well as generically.
Simvastatin
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate | |
Zocor | |
monograph | |
a692030 | |
US FDA:link | |
D (AU) X (US) | |
Prescription Only (S4) (AU) P (UK) -only (US) | |
Oral | |
5% | |
95% | |
Hepatic (CYP3A4) | |
2 hours for simvastatin and 1.9 hours for simvastatin acid | |
Renal 13%, faecal 60% | |
79902-63-9 Y | |
C10AA01 | |
CID 54454 | |
APRD00104 | |
49179 Y | |
AGG2FN16EV Y | |
D00434 Y | |
CHEBI:9150 Y | |
CHEMBL1064 Y | |
C25H38O5 | |
418.566 g/mol | |
eMolecules & PubChem | |
InChI[show] |
Simvastatin 79902-63-9