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High quanlity 99% Pure Glibenclamide Powder
High quanlity 99% Pure Glibenclamide Powder
Supplier Info
[China Supplier]
Contact Person : Mr. Li Qiang
Tel : 0086-029-89188938
Fax : 0086-029-88765269
Product Detail
Specifications 1.Glybenzcyclamide 2.White crystalline powder 3.Professional manufacture 4.High quality competitive price

Application

    Acarbose is an anti-diabetic drug used to treat type 2 diabetes mellitus and, in some countries, prediabetes. It is sold in Europe under the brand name Glucobay (Bayer AG), in North America as Precose (Bayer Pharmaceuticals), and in Canada as Prandase (Bayer AG). It is an inhibitor of alpha glucosidase, an enteric enzyme that releases glucose from larger carbohydrates.

Function and Usage

     Hypoglycaemic. Inhibit decomposition of glycogen and Gluconeogenesis, reduce glucoses production and output in liver;Besides, it can strengthen pancreass sensitivity to insulin and consume more sugar,reducing FPG and P2hPG.

    For the second-generation sulfonylurea drugs, there is a strong role in lowering blood glucose, its hypoglycemic effect than D-860 Strong 100-fold. Fasting blood glucose after treatment compared with postprandial blood glucose significantly decreased, respectively, reduced by about 35%, and 21% or less.

    Easily absorbed from the gastrointestinal tract, plasma protein binding rate is high.Fall blood sugar function strong, Glyburide capsule: its role a toluene sulfonylurea urea butyl 100 times stronger. Oral 30 minutes later appeared for about 16 ~ role 24 hours. Easily absorbed from the gastrointestinal tract, plasma protein binding rate is high. T1/2 about 10 h. Almost all by hepatic metabolism, the main metabolites hypoglycemic activity is weak. About 50% of metabolites from urine discharge, and another 50% by bile into debris. Glyburide piece: this product is lowering blood sugar pills.

     1. Stimulate pancreatic beta cells secrete insulin, a prerequisite, there is still a beta cell synthesis and secretion of insulin function;

    2. Through the increase insulin levels for the liver or portal vein direct action, inhibit liver glycogen decomposition and glycogen vision, liver function was born generation and output glucose reduced;

    3. Also may increase the organization for pancreatic insulin sensitiity and sugar (mainly through the use of possible receptors, therefore, the role) function is reduced fasting blood sugar and blood glucose after a meal. 

Analysis

Name

Glyburide

Appearance

White crystalline powder

Cas   

10238-21-8

MF     

C23H22ClN3O5S

Mol. mass

487.9559

Grade

Medicine grade

Assay                   

99.6%

Density

1.376g/cm3

EINECS

233-570-6

Usage

Hypoglycemic

Delivery

1 to 3 days

Package

1kg/Aluminum foil bag,25kg/drum

Packaging

Shipping

High quanlity 99% Pure Glibenclamide Powder

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