Colistin (Polymyxin E) is a polymyxin produced by a bacterium of the genus Bacillus (B. polymyxa var. colistinus). Colistin is effective against most Gram-negative bacilli such as E-coil, Serpulina Hyodysenteriae, Salmonella Pullorum and also effective on Pseudomonas aeruginosa.
[Specification]
Test Items | Specifications |
Appearance | White or almost white, hygroscopic powder |
Specific Rotation | -63º to -73º |
pH | 4.0 to 6.0 |
Loss on Drying | 3.5% max |
Sulphate (Dried Basis) | 16.0 to 18.0 % |
Sulphated Ash | 1.0% max |
Total Impurities | 23.0% max |
Assay HPLC (Dried Basis) | Not less than 77.0% |
Potency (Dried Basis) | Not less than 19,000 IU/mg |
[Features]
1) Improve growth performance of livestock & poultry;
2) Inhibit Gram-negative bacteria at growth duration or dormancy state;
3) Prevent bacterial diarrhea and synergistic effects with other antibiotics;
4) No cross tolerance with broad range of antibacterial agent;
[Recommended Dosage]g/ton complete feed
Target Animals | Colistin Sulfate | Withdrawal Period | |
Swine | < 2 months | 2(60MU) – 20(600MU) | 7 Days |
2-4 months | 2(60MU) – 40(1200MU) | ||
Poultry | < 70 days | 2(60MU) – 20(600MU) | |
Cattle | < 3 months | 5(150MU) – 40(1200MU) | |
Note: 1μg of Colistin is equivalent to 30 IU of Colistin; MU = Million Unit |
[Precaution]
1) May cause damage in kidney function by overdosing;
2) Prohibited to use during laying period.
[Packing]20kg drum
[Validity]Two year under dry and unopened conditions
CVP EP Standard Colistin Sulphate