Tacrolimus CAS NO:104987-11-3 assay:98%min in stock. FK-506 inhibits Ca2+-dependent transcription of lymphokine genes in T cells. FK-506 (0.1 to 300 nM) concentration dependently inhibited histamine release from lung parenchymal mast cells activated by anti-IgE. FK-506 was more potent in lung mast cells than in basophils (IC50 = 1.13 +/- 0.46 nM vs 5.28 +/- 0.88 nM; p less than 0.001), whereas ...
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