L-Ornithine L-Aspartate (LOLA) Fermented an important API a compound of L-Ornithine and L-Aspartate, not a mixture

L-Ornithine L-Aspartate (LOLA) is an important API curing hepatitis. It is a compound of Ornithine and Aspartate, not a mixtureWe use fermentation way to produce this product, not chemical reaction.

AJI97/DAB10

Main Function: L-ornithine-L-aspartate (LOLA) is a key metabolite in liver function, crucial in converting ammonia to urea and glutamine, thereby supporting healthy levels of ammonia.

Pharmacology:

 

L-Ornithine and L-Aspartate are important substrates in the metabolic conversion of ammonia to urea and glutamine, respectively. L-Ornithine-L-Aspartate (LOLA) thus provides for both of these ammonia detoxification pathways by generating L-Ornithine and L-Aspartate in vivo. Controlled clinical trials suggest that L-Ornithine-L-Aspartate (LOLA) reduce ammonia levels significantly.

As L-ornithine-L-aspartate exerts its action in the metabolic cycles of the liver, elevated blood ammonia levels are rapidly lowered. The capacity of detoxification, particularly of the urea cycle, is enhanced and the energy balance improved. Liver dysfunctions are favorably influenced, and the regeneration of the liver cells is promoted.

	Enzymatic LOLA	Fermented LOLA
Production Technology	Enzyme Hydrolysis  L-Arginine + L-Aspartic acid → LOLA	Fungi Fermentation                 reaction Corn Starch→L-Ornithine + L-Aspartic acid→LOLA
Magnesium residue	The enzyme hydrolysis of L-Arginine needs magnesium as catalyst, the final product will have magnesium residue.	None
Urea residue	When L-Arginine is   enzyme hydrolyzed to L-Ornithine, urea is the byproduct, and might remain in the final LOLA.	None
Source and heavy metals residue	The enzyme is extracted from animal liver, and the L-Arginine can be hydrolyzed from animal feathers, which contains higher residue of heavy metals same as most hydrolyzed amino acids.	Fermented from corn starch directly, no animal source material needed, and the residue of heavy metals is very low. The only residue of the fermented LOLA is very little proteins produced during the starch fermentation.
Enzyme residue	During the extraction of enzyme, some other enzymes might be extracted together with the Arginine enzyme, and will remain in the final LOLA.	None

L-Ornithine L-Aspartate--Fermented, not a mixture