For the incompleted injury of nerve cell be caused by all the kinds of Neurological Lesion( whatever character).

Composition:

The active ingredient is mNGF. Contain the 5% Mannitol and 0.1% human serum albumin (HSA) act as protective.

Description:

  White freeze-dry tiny loose particles. Changes to be colourless clear liquid after be dissolved according to the volume of the marking, should not find the Foreign Body, turbidness and sediment.

Pharmacology:

   The result of the test in the body of Rat indicate: this drug can ameliorate the Body dysfunction be caused by Rat toxic diseases of peripheral nerve be made of hexanedione and acrylamid,it can shorten the delitescence of nervimuscular action potential. And it could advance the range of nervimuscular action potential.

The result of Histopathology indicates: this drug can abate the incidence of medullary-sheath tumefaction of creatural nervi tibialis and reduce the number of nerve fibers of denature femur.

The result above indicates that this drug can accelerate the renew of nerve injury.

Clinical application: Toxic diseases of peripheral nerve by n-hexane.

1. peripheral nerve injury and peripheral nerve disease. Such as Optic nerve injury, neurotmesis and toxicosis by n-hexane etc.

2. Craniocerebral trauma

3. acute cerebrovascular disease, brain atrophy, parkinsonism, Alzheimer's disease.

4. Spinal injury

5. Hypoxic Ischemic Encephalopathy, cerebral palsy.

Dosage and Administration:

   Use 2ml water for injection to dissolve it. intramuscular injection. One time a day, One botlle20μgeverytime. One course of the treatment have four weeks. The successive administration could be used as directed by a physician according to the patient's condition.

Adverse Reaction:

1. No serious adverse reaction. No functional lesion of liver, kidney, heart in clinical trial.

2. Injection site hurts(incidence rate: about 85%) or crura of the injection site hurtsincidence rate: about 29%after Medication, it need not to dispose commonly. Several which is on the basis of obvious serious symptoms could have the analgesic for remission.

3. Theres some other symptom such as the vertigo and insomnia every once in a while. No significant difference in the compare of incidence rate and placebo group.

Contraindication:

Forbidden for the people have the highly allergic to this drug.

Attentions:

1. Cautious use for the allergic people.

2.This drug should be consolute after be dissolved water for injection and be shaked. Do not sue if find the floccule, turbidness and sediment.

3.Carefully check the Vial before use. Do not use if theres abnormal condition  such as the rift and breakage.  

4.Please consult a doctor in time if theres any indisposed symptom in the use

Medication for the pregnant woman & women during lactation:

The drug could promote upgrowth of the neuron, advice that should be Cautious use for the pregnant woman & women during lactation.

Specifications:

Contain mNGF 20μg / Vial,biological activity≥9000AU

Storage:

2 to 8 centigrade Keeping in Dark

Packing:

20μg mNGF(≥9000AU)/ Vial

Valid Period:

   30 Months

SFDA approval number:

      H.M.L.N. S20060051

Mouse Nerve Growth Factor for In Jection(mNGF)